Product & ReviewsAntibodies
RAT ANTI MOUSE CD70:RPE
Product Details
- Cat. No.
- MCA2302PE
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
Rat anti Mouse CD70 antibody, clone FR70 recognizes mouse CD70, a 30-33 kDa type II transmembrane protein belonging to the TNF superfamily. CD70 is not expressed on resting T cells and B cells but expression is induced on activation. Interaction of CD70 with its ligand CD27 is reported to play an important role in T cell co-stimulation and the regulation of T-dependant B cell activation and antibody production.Clone FR70 is reported to block the functions of CD70 and has been used to block the interactions between CD27 and CD70 (Oshima et al.).
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Isotype: IgG2b
Handling
- Quantity: 100 TESTS
- Storage: +4ºC DO NOT FREEZE
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide, 1% BSA, 5% Sucrose
Applications
- Flow Cytometry (FC)
- Immunoprecipitation (IP)