RAT ANTI MOUSE CD70:RPE

Rat anti Mouse CD70 antibody, clone FR70 recognizes mouse CD70, a 30-33 kDa type II transmembrane protein belonging to the TNF superfamily. CD70 is not expressed on resting T cells and B cells but expression is induced on activation. Interaction of CD70 with its ligand CD27 is reported to play an important role in T cell co-stimulation and the regulation of T-dependant B cell activation and antibody production.Clone FR70 is reported to block the functions of CD70 and has been used to block the interactions between CD27 and CD70 (Oshima et al.).

• Clonality: Monoclonal
• Host: Rat
• Reactivity: Mouse
• Isotype: IgG2b

• Quantity: 100 TESTS
• Storage: +4ºC DO NOT FREEZE
• Buffer: Phosphate buffered saline, 0.09% Sodium Azide, 1% BSA, 5% Sucrose

• Flow Cytometry (FC)
• Immunoprecipitation (IP)