Product & ReviewsAntibodies
RAT ANTI MOUSE CD8 ALPHA
Product Details
- Cat. No.
- MCA609GA
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
Rat anti Mouse CD4 antibody used for the detection of CD8 positive lymphocytes
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Description
Rat anti mouse CD8α, clone KT15, recognizes the alpha chain of mouse CD8. CD8 is a heterodimeric protein composed of disulphide-linked CD8α and CD8β chains that is expressed primarily on cytotoxic T-cells. CD8 functions in the interaction with MHC Class I-bearing targets and plays a role in T-cell-mediated killing (Nakauchi , H. et al., 1985 & Nakauchi, H. et al., 1987).Clone KT15 is reported to block T-cell-mediated cytotoxicity in in vitro assays (Zeis, M. et al., 2002).
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Isotype: IgG2a
Handling
- Quantity: 0.1 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- Flow Cytometry (FC)
- Immunofluorescence (IF)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
