Product & ReviewsAntibodies

RAT ANTI MOUSE CD8 ALPHA

Product Details

Cat. No.
MCA609GA
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
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Bio-Rad

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Description

Rat anti mouse CD8α, clone KT15, recognizes the alpha chain of mouse CD8. CD8 is a heterodimeric protein composed of disulphide-linked CD8α and CD8β chains that is expressed primarily on cytotoxic T-cells. CD8 functions in the interaction with MHC Class I-bearing targets and plays a role in T-cell-mediated killing (Nakauchi , H. et al., 1985 & Nakauchi, H. et al., 1987).Clone KT15 is reported to block T-cell-mediated cytotoxicity in in vitro assays (Zeis, M. et al., 2002).

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Isotype: IgG2a

Handling

  • Quantity: 0.1 mg
  • Storage: +4ºC, -20ºC if preferred
  • Buffer: Phosphate buffered saline, 0.09% Sodium Azide

Applications

  • Flow Cytometry (FC)
  • Immunofluorescence (IF)
  • Immunohistochemistry (Frozen Sections) (IHC (Fr))
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