Product & ReviewsAntibodies
RAT ANTI MOUSE TNF ALPHA
Product Details
- Cat. No.
- MCA1488
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
Recombinant mouse TNF alpha detected with Rat anti Mouse TNF alpha (MCA1488)
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Description
Rat anti Mouse TNF alpha antibody, clone MP6-XT22 recognizes mouse tumor necrosis factor alpha (TNF alpha), a ~17 kDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF alpha forms dimers and trimers, and is also found as a ~26 kDa integral membrane protein. Mouse TNF alpha has cytolytic activity against many tumor cell lines, and has an important immunoregulatory role.Rat anti Mouse TNF alpha antibody, clone MP6-XT22 is reported to neutralize the effects of mouse TNF alpha (Gaup et al. 2008 and Yang et al. 1995).
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse, Rat
- Isotype: IgG1
Handling
- Quantity: 0.5 mg
- Storage: +4ºC, -20ºC if preferred
- Buffer: Phosphate buffered saline, 0.09% Sodium Azide
Applications
- ELISA (ELISA)
- Flow Cytometry (FC)
- Immunohistochemistry (Frozen Sections) (IHC (Fr))
