RAT ANTI MOUSE TWEAK

Rat anti Mouse TWEAK antibody, clone MTW-1 recognizes mouse TWEAK (TNF-like weak inducer of apoptosis) a type II transmembrane TNF superfamily member. TWEAK binds to the TWEAK receptor FN14 (TWEAK-R) to weakly induce apoptosis in some cell types. It is involved in the induction of inflammatory cytokines. This cytokine also promotes proliferation and migration of endothelial cells and acts as a regulator of angiogenesis. TWEAK is expressed on a broad range of adult and foetal tissues. Rat anti Mouse TWEAK antibody, clone MTW-1 blocks ligand binding in vitro (Nakayama et al. 2003).

• Clonality: Monoclonal
• Host: Rat
• Reactivity: Mouse
• Isotype: IgG1

• Quantity: 0.1 mg
• Storage: +4ºC, -20ºC if preferred
• Buffer: Phosphate buffered saline, 0.09% Sodium Azide

• Flow Cytometry (FC)