Product & ReviewsAntibodies
Rb Antibody
Product Details
- Cat. No.
- 200149
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Retinoblastoma-associated protein (Rb) is a key regulator of entry into cell division that acts as a tumor suppressor. Rb is directly involved in the heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Defects in Rb are a cause of retinoblastoma, bladder cancer and osteogenic sarcoma.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat, Xenopus
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Rb.
- Isotype: Rabbit Ig
- Gene: P06400, NP_000312
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)