Product & ReviewsAntibodies
RBBP6 Antibody
Product Details
- Cat. No.
- 251916
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
E3 ubiquitin-protein ligase RBBP6 (RBBP6) is an E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. RBBP6 plays a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in the increase of MDM2-mediated ubiquitination and degradation of p53/TP53. RBBP6 functions as negative regulator of p53/TP53, leading to both apoptosis and cell growth.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RBBP6.
- Isotype: Rabbit Ig
- Gene: Q7Z6E9
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)