Product & ReviewsAntibodies
RNA Pol II CTD phospho Thr4 rat antibody (mAb) (Clone 6D7)
Product Details
- Cat. No.
- 61361
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
RNA pol II (RNA polymerase II) is a complex of 12 proteins that participates in transcription, mRNA processing, and transcription-coupled DNA repair. RNA polymerase II is distinguished by its large carboxyl-terminal repeat domain (CTD), composed of repeats of the consensus heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Polo-like kinase 3 (plk3) has been reported to phosphorylate Thr4 which may be required for transcriptional elongation.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Not Species Specific, Human
- Clone: 6D7
- Isotype: IgG2b
Handling
- Quantity: 100 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Chromatin Immunoprecipitation (ChIP)
- Immunofluorescence (IF)
- Western Blotting (WB)