Product & ReviewsAntibodies

RNA Pol II CTD phospho Thr4 rat antibody (mAb) (Clone 6D7), sample

Product Details

Cat. No.
61362
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
Active Motif

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Description

RNA pol II (RNA polymerase II) is a complex of 12 proteins that participates in transcription, mRNA processing, and transcription-coupled DNA repair. RNA polymerase II is distinguished by its large carboxyl-terminal repeat domain (CTD), composed of repeats of the consensus heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Polo-like kinase 3 (plk3) has been reported to phosphorylate Thr4 which may be required for transcriptional elongation.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Not Species Specific, Human
  • Clone: 6D7
  • Isotype: IgG2b

Handling

  • Quantity: 10 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Chromatin Immunoprecipitation (ChIP)
  • Immunofluorescence (IF)
  • Western Blotting (WB)
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