RNF34 Rabbit pAb
Product Details
- Cat. No.
- A8517
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - RNF34 antibody (A8517)
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Description
The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
