Product & ReviewsAntibodies
RNF8 Rabbit pAb
Product Details
- Cat. No.
- A7302
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - RNF8 antibody (A7302)
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Description
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
