Product & ReviewsAntibodies

ROR gamma T antibody

Product Details

Cat. No.
orb385620
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Biorbyt

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Description

Rabbit polyclonal antibody to ROR gamma T whose expression can be detected in the heart but it is highly expressive in the brain and atria. It is found in the nuclear body. It is a negative regulator of adipocyte differentiation through the regulation of early phase gene expression; such as MMP3 and controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity. This protein is extensively considered to have intrinsic transcriptional activity along with some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols); enhancing or repressing the transcriptional activity respectively.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat
  • Clone: NULL
  • Conjugate: Unconjugated
  • Isotype: IgG
  • Gene: NULL

Handling

  • Quantity: 100 ?g; 200 ?g
  • Storage: Store at 4°C for up to two weeks. For long term storage; aliquot and store at -20°C; avoid freeze/thaw cycles.
  • Buffer: 10 mM PBS; 0.02% sodium azide

Applications

  • Immunofluorescence (IF)
  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
  • Western Blotting (WB)
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