Product & ReviewsAntibodies

ROR1 antibody

Product Details

Cat. No.
orb11664
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Biorbyt

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Description

Rabbit polyclonal to ROR1. ROR1(receptor tyrosine kinase-like orphan receptor 1); also known as neurotrophic tyrosine kinase; receptor-related 1 (NTRKR1); Tyrosine-protein kinase transmembrane receptor ROR1; is a member of thereceptor tyrosine kinase-like orphan receptor (ROR) family. NTRKR1 encodes a predicted 937-amino acid protein. A 6-kb NTRKR1 mRNA is expressed strongly in human heart; lung; and kidney; but weakly in the CNS. However; a truncated 2.4-kb mRNA lacking extracellular and transmembrane domains was strongly expressed in fetal and adult CNS and in a variety of human cancers; including those originating from CNS or PNS neuroectoderm. The protein encoded by this gene is a receptor tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat
  • Clone: NULL
  • Conjugate: Unconjugated
  • Isotype: IgG
  • Gene: NULL

Handling

  • Quantity: 100 ?g; 200 ?g
  • Storage: Store at 4°C for up to two weeks. For long term storage; aliquot and store at -20°C; avoid freeze/thaw cycles.
  • Buffer: 10 mM PBS; 0.02% sodium azide

Applications

  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
  • Western Blotting (WB)
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