Product & ReviewsAntibodies
RORC Antibody
Product Details
- Cat. No.
- 200218
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Nuclear receptor ROR-gamma (RORC) is a nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. RORC is a key regulator of cellular differentiation, immunity, peripheral circadian rhytm as well as lipid, steroid, xenobiotics and glucose metabolism. Two isoforms are known for RORC: isoform 1 is widely expressed in many tissues, including liver and adipose, and highly expressed in skeletal muscles. Isoform 2 is primarily expressed in immature thymocytes.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: Recombinant human RORC
- Isotype: Rabbit Ig
- Gene: P51449
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)