Product & ReviewsAntibodies
Sf3b3 mouse antibody (mAb) (Clone 1YO-1B10)
Product Details
- Cat. No.
- 61345
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Sf3b3 (splicing factor 3b, subunit 3, 130kDa) is a subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Clone: 1YO-1B10
- Isotype: IgG1k
Handling
- Quantity: 100 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunoprecipitation (IP)
- Western Blotting (WB)