Product & ReviewsAntibodies

Sf3b3 mouse antibody (mAb) (Clone 1YO-1B10), sample

Product Details

Cat. No.
61346
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Active Motif

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Description

Sf3b3 (splicing factor 3b, subunit 3, 130kDa) is a subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Mouse
  • Clone: 1YO-1B10
  • Isotype: IgG1k

Handling

  • Quantity: 10 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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