Product & ReviewsAntibodies
Shank1 Antibody
Product Details
- Cat. No.
- 250856
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
SH3 and multiple ankyrin repeat domains protein 1 (Shank1) is an adaptor protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, as well as in the actin based cytoskeleton. Shank1 plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Shank1 is expressed in the brain, particularly in the amygdala, hippocampus, substantia nigra and thalamus.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Shank1.
- Isotype: Rabbit Ig
- Gene: Q9Y566
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)