Protein-tyrosine phosphatase SHP-1 (SHP-1, PTP-1C) plays a key role in hematopoiesis. The PTPase activity of SHP-1 directly links growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions interact with other cellular components to modulate its own phosphatase activity against interacting substrates.
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SHP-1.
- Isotype: Rabbit Ig
- Gene: P29350
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)