Product & ReviewsAntibodies

Sialoadhesin antibody

Product Details

Cat. No.
orb318719
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Biorbyt

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Description

Rabbit polyclonal antibody to sialoadhesin also known as SIGLEC1; whose expression can be detected in the liver Kupffer cells and lamina propria of colon and lung and colon; but is highly expressive in the spleen and perivascular macrophages in the brain. It is found in the cell membrane. This protein extensively acts as an endocytic receptor mediating clathrin dependent endocytosis and macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes; including granulocytes; monocytes; natural killer cells; B-cells and CD8 T-cells.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat
  • Clone: NULL
  • Conjugate: Unconjugated
  • Isotype: IgG
  • Gene: 6614

Handling

  • Quantity: 100 ?g; 200 ?g
  • Storage: Store at 4°C for up to two weeks. For long term storage; aliquot and store at -20°C; avoid freeze/thaw cycles.
  • Buffer: 10 mM PBS; 0.02% sodium azide

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P))
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