Product & ReviewsAntibodies
SIGLEC5 Rabbit pAb
Product Details
- Cat. No.
- A4250
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - SIGLEC5 antibody (A4250)
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Description
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
