Product & ReviewsAntibodies

SIRT1 mouse antibody (mAb) (Clone 2G1/F7), sample

Product Details

Cat. No.
39354
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Active Motif

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Description

SIRT1 is a member of the Sirtuin family of proteins related to the yeast Sir2 protein. Like Sir2 and other Sirtuins, SIRT1 is an NAD-dependent histone and protein deacetylase. SIRT1 catalyzes the removal of acetyl groups from a variety of protein substrates (NBS1, P53, Ku70, etc) as well as from lysine 16 of histone H4. SIRT1 is involved in the regulation of a number of cellular processes, including transcription, metabolism, DNA repair and aging.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Clone: 2G1/F7
  • Isotype: IgG1

Handling

  • Quantity: 10 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Immunofluorescence (IF)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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