SIRT5 Antibody
Product Details
- Cat. No.
- 254290
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Chicken
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Description
The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.
Biological Information
- Clonality: Polyclonal
- Host: Chicken
- Reactivity: Human, Mouse
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human SIRT5.
- Isotype: Chicken Ig
- Gene: NP_036373
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)