Product & ReviewsAntibodies
SKP2 (6G9D) Antibody
Product Details
- Cat. No.
- 252839
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Skp2 (S-phase kinase-associated protein 2) is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Skp2 specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of SKP2(aa1-130) expressed in E. coli.
- Clone: 6G9D10
- Isotype: Mouse IgG1
- Gene: Q13309
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)