Product & ReviewsAntibodies
Skp2 Antibody
Product Details
- Cat. No.
- 251467
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Skp2 (S-phase kinase-associated protein 2) is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Skp2 specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Skp2.
- Isotype: Rabbit Ig
- Gene: Q13309
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)