Product & ReviewsAntibodies
SLC8A1 Antibody
Product Details
- Cat. No.
- 253215
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Ca2+ plays a critical role in intracellular signaling and thus regulation of calcium balance is critical for the maintenance of this signaling function. The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling. NACX-1 may also be a target for protection of the heart and brain from ischemia and reperfusion injury.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rabbit (Lapine), Rat
- Antigen: KLH-conjugated peptide encompassing a sequence within the N-term region of rabbit sodium calcium exchanger 1.
- Clone: 6H2
- Isotype: Mouse IgG2b
- Gene: Q01728
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)