Product & ReviewsAntibodies
Smad2/3 Antibody
Product Details
- Cat. No.
- 251894
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
SMAD family member 2 (SMAD2/3) is receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. SMAD2/3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. SMAD2/3 acts as a tumor suppressor in colorectal carcinoma.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Smad2/3.
- Isotype: Rabbit Ig
- Gene: Q15796; P84022
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)