SMARCA4 / BRG1 rat antibody (mAb) (Clone 3G4), sample
Product Details
- Cat. No.
- 39808
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
BRG1 (Brahma-related gene-1, SNF2b) is the central catalytic ATPase subunit of numerous chromatin-remodeling complexes, including SWI/SNF. These complexes are able to use energy from ATP hydrolysis to physically disrupt chromatin architecture of target promoters and facilitate the binding of transcription factors to nucleosomal DNA. BRG1 is a co-regulator of transcription and has been implicated in the activation and repression of gene expression through the modulation of chromatin in various tissues and physiological conditions. This protein plays a major role in many cellular processes such as DNA replication, repair and recombination. Mammalian BRG1 is usually associated with approximately 10-12 BAF subunits or other proteins involved in regulation of gene expression.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Human, Mouse
- Clone: 3G4
- Isotype: IgG2b
Handling
- Quantity: 10 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Immunofluorescence (IF)
- Western Blotting (WB)