SOCS1 Rabbit pAb
Product Details
- Cat. No.
- A0820
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Mouse, Rat
- Antigen: IgG
Handling
- Specificity: 5
Applications
- Flow Cytometry (FC)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)
Western blot analysis
Value for money. Good product. I would recommend this antibody for detection of SOCS1 in mouse spleen lysates.
Review Date: 13 May 2021 | ABclonal Technology