SOCS3 Rabbit pAb
Product Details
- Cat. No.
- A0694
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
Handling
- Specificity: 5
Applications
Western blot
Western blot analysis of extracts of mouse spleen yields perfect blot results at 1:1000 dilution. Band visible at 25kDa.
Review Date: 14 May 2021 | ABclonal Technology