SOD1 (6F5) Antibody
Product Details
- Cat. No.
- 252889
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
SOD1 (Superoxide dismutase 1) destroys free radicals which are normally produced within the cells and which are toxic to biological systems. SOD1 catalyzes the following reaction: 2 superoxide + 2 H+ = O2 + H2O2. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1). ALS1 is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of cases leading to familial forms.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Antigen: Purified recombinant fragment of human SOD1 expressed in E. coli.
- Clone: 6F5
- Isotype: Mouse IgG1
- Gene: P00441
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Flow Cytometry (FC)
- Immunofluorescence (IF)
- Western Blotting (WB)