SOD1 Antibody
Product Details
- Cat. No.
- 251450
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
SOD1 (Superoxide dismutase 1) destroys free radicals which are normally produced within the cells and which are toxic to biological systems. SOD1 catalyzes the following reaction: 2 superoxide + 2 H+ = O2 + H2O2. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1). ALS1 is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of cases leading to familial forms.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SOD1.
- Isotype: Rabbit Ig
- Gene: P00441
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blotting (WB)