Product & ReviewsAntibodies
STAT3 (3B5) Antibody
Product Details
- Cat. No.
- 253081
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
STAT3 (Signal transducer and activator of transduction 3) is a transcription factor that binds to the interleukin-6 responsive elements located in the promoter regions of various acute-phase protein genes. STAT3 is activated by IL-31 receptor pathway. Active STAT3 consists in homodimers or heterodimers with family member STAT1 and serine phosphorylation is important for DNA-binding and transcriptional activities. Defects in STAT3 are the cause of hyperimmunoglobulin E recurrent infection syndrome (Job syndrome).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Monkey, Mouse
- Antigen: Purified recombinant fragment of human STAT3 expressed in E. coli.
- Clone: 3B5
- Isotype: Mouse IgG1
- Gene: P40763
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blotting (WB)