Product & ReviewsAntibodies

STAT3 (7G3H) Antibody

Product Details

Cat. No.
252842
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Abbiotec

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Description

STAT3 (Signal transducer and activator of transduction 3) is a transcription factor that binds to the interleukin-6 responsive elements located in the promoter regions of various acute-phase protein genes. STAT3 is activated by IL-31 receptor pathway. Active STAT3 consists in homodimers or heterodimers with family member STAT1 and serine phosphorylation is important for DNA-binding and transcriptional activities. Defects in STAT3 are the cause of hyperimmunoglobulin E recurrent infection syndrome (Job syndrome).

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: "Purified recombinant fragment of STAT3 expressed in E. coli. <br>"
  • Clone: 7G3H4
  • Isotype: Mouse IgG1
  • Gene: P40763

Handling

  • Quantity: 0.1 ml
  • Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.

Applications

  • Western Blotting (WB)
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