Product & ReviewsAntibodies
STAT3 Antibody
Product Details
- Cat. No.
- 251107
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
STAT3 (Signal transducer and activator of transduction 3) is a transcription factor that binds to the interleukin-6 responsive elements located in the promoter regions of various acute-phase protein genes. STAT3 is activated by IL-31 receptor pathway. Active STAT3 consists in homodimers or heterodimers with family member STAT1 and serine phosphorylation is important for DNA-binding and transcriptional activities. Defects in STAT3 are the cause of hyperimmunoglobulin E recurrent infection syndrome (Job syndrome).
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse, Pig (Swine), Rat
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human STAT3.
- Isotype: Rabbit Ig
- Gene: P40763
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)