Product & ReviewsAntibodies

STAT4 Rabbit mAb

Product Details

Cat. No.
A4523
Type
Primary Antibody
Clonality
Monoclonal
Host
Rabbit
ABclonal Technology

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Description

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]

Biological Information

  • Clonality: Monoclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rat

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