Surfactant protein D (10B2) Antibody
Product Details
- Cat. No.
- 250403
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is approximately 700 ng/ml in healthy individuals. This antibody is specific for SP-D from amniotic fluid, serum and bronchioalveolar lavage. The antibody blocks SP-D binding to GP-340 but not to carbohydrates.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Native human SP-D purified from late pregnancy amniotic fluid
- Clone: 10B2
- Isotype: Mouse IgG2a/k
- Gene: P35247
Handling
- Quantity: 0.2 mg
- Storage: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)