Product & ReviewsAntibodies
Survivin (2H5H) Antibody
Product Details
- Cat. No.
- 252746
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Survivin (Apoptosis inhibitor survivin) is a component of the chromosomal passenger complex (CPC), a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation. CPC is required for chromatin-induced microtubule stabilization and spindle assembly. Survivin interacts with tubulin and inhibits caspase-3 and caspase-7. Survivin is abundantly expressed in adenocarcinoma and high-grade lymphomas.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Purified recombinant fragment of Survivin expressed in E. coli.
- Clone: 2H5H2
- Isotype: Mouse IgG1
- Gene: O15392
Handling
- Quantity: 0.1 ml
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)