Product & ReviewsAntibodies
SUV39H1 mouse antibody (mAb) (Clone MG44)
Product Details
- Cat. No.
- 39785
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Drosha is an RNAse III enzyme that is involved in the process of generating microRNA (miRNA). miRNA interacts with the RNA-induced silencing complex (RISC) to cleave mRNA and thus downregulate gene expression. Drosha is a double stranded RNAse and part of the Microprocessor complex. Other RNAse III enzymes include Dicer and Argonaute. Drosha initiates processing of the miRNA precursor (pri-miRNA) in the nucleus, which is then exported to the cytoplasm and further cleaved by Dicer into a mature miRNA.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse
- Clone: MG44
- Isotype: IgG1
Handling
- Quantity: 100 ug
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Chromatin Immunoprecipitation (ChIP)
- Immunoprecipitation (IP)
- Western Blotting (WB)