Product & ReviewsAntibodies

SUV39H1 mouse antibody (mAb) (Clone MG44)

Product Details

Cat. No.
39785
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Active Motif

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Description

Drosha is an RNAse III enzyme that is involved in the process of generating microRNA (miRNA). miRNA interacts with the RNA-induced silencing complex (RISC) to cleave mRNA and thus downregulate gene expression. Drosha is a double stranded RNAse and part of the Microprocessor complex. Other RNAse III enzymes include Dicer and Argonaute. Drosha initiates processing of the miRNA precursor (pri-miRNA) in the nucleus, which is then exported to the cytoplasm and further cleaved by Dicer into a mature miRNA.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Mouse
  • Clone: MG44
  • Isotype: IgG1

Handling

  • Quantity: 100 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Chromatin Immunoprecipitation (ChIP)
  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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