Product & ReviewsAntibodies
Synaptobrevin Antibody
Product Details
- Cat. No.
- 253220
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Synaptobrevin (VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer’s disease.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Bovine, Hamster, Human, Mouse, Pig (Swine), Rat
- Antigen: Synaptic immunoprecipitate (crude) from human brain.
- Clone: SP10
- Isotype: Mouse IgM
- Gene: P23763
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)