Product & ReviewsAntibodies
Syntaxin Antibody
Product Details
- Cat. No.
- 253224
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion. Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have been correlated with schizophrenia.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Horse (Equine), Human, Pig (Swine), Rat
- Antigen: Synaptic immunoprecipitate (crude) from human brain.
- Clone: SP8
- Isotype: Mouse IgG1
- Gene: Q16623
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)