Product & ReviewsAntibodies
TAO2 (Ser181) Antibody
Product Details
- Cat. No.
- 252586
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK. This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs. Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Bovine, Dog (Canine), Human, Mouse, Rat, Xenopus, Zebrafish
- Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser181 of rat TAO2.
- Isotype: Rabbit Ig
- Modifications: Phosphospecific Antibody
- Gene: Q9UL54
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)