TBX21 Rabbit pAb
Product Details
- Cat. No.
- A4682
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - TBX21 antibody (A4682)
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
