TCR Vα24-PE, C15, 1 mL, ASR
Product Details
- Cat. No.
- IM2283
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Also called TCRAV24S1 (according to the nomenclature from Arden et al.)Vα24 is the only described member of the subfamily of the T cell receptor. It has been shown to be expanded in a clonal fashion in the CD3+ CD8- CD4- cell population in PBL of several donors. It is expressed by 0.4% to 1% of peripheral CD3+ cells from normal blood. An invariant Vα24/Vβ11 T cell receptor is expressed in all individuals by clonally expanded CD4– CD8– T cells, reactive to bacterial antigens. This unique lymphocyte population restricted by the CD1d molecule recognition has been identified as the natural killer T (NKT) cells. The IGRa02 sequence is also referred to as TRAV10 (based on the IMGT gene nomenclature).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: TCR Vα24
- Clone: C15
- Conjugate: PE
- Isotype: IgG1
Handling
- Quantity: 1 mL
Applications
- Flow Cytometry (FC)