TCR Vβ11-FITC, C21, 1 mL, ASR
Product Details
- Cat. No.
- IM1586
- Type
- Flow Cytometry Reagents
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Also called TCRBV11S1Vβ11 is the human variable β11 chain of the T cell receptor. Two Vβ11 sequences are described, PL3.12 and PH15. These sequences differ only in their leader sequence and therefore lead to the same mature protein. An invariant Vα24/Vβ11 T cell receptor is expressed in all individuals by clonal expanded CD4– CD8– T cells, reactive to bacterial antigens. This unique lymphocyte population restricted by the CD1d molecule recognition has been identified as the natural killer T (NKT) cells. Vβ11 is expressed by 0.4% to 0.9% of peripheral CD3+ cells in normal blood. This sequence is also referred to as TRBV25-1 (based on the IMGT gene nomenclature).
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: TCR Vβ11
- Clone: C21
- Conjugate: FITC
- Isotype: IgG2a
Handling
- Quantity: 1 mL
Applications
- Flow Cytometry (FC)