Product & ReviewsAntibodies

Tet2 mouse antibody (mAb) (Clone 21F11)

Product Details

Cat. No.
61389
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Active Motif

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Description

Tet2 (tet methylcytosine dioxygenase 2) catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). Plays an important role in myelopoiesis. The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation and differentiation in the case of inflammation by regulating gene expression and macrophage differentiation.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Clone: 21F11
  • Isotype: IgG1k

Handling

  • Quantity: 100 ug
  • Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Applications

  • Immunoprecipitation (IP)
  • Western Blotting (WB)
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