Product & ReviewsAntibodies

TGF-alpha Antibody

Product Details

Cat. No.
250875
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Abbiotec

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Description

Transforming growth factor (TGF-alpha, TGF-a, EGF-like TGF) is a polypeptide growth factor that shares significant structural and functional homology with epidermal growth factor (EGF). TGF is synthesized as a 160 amino acid transmembrane precursor molecule from which the mature 50 amino acid TGF alpha peptide is secreted following proteolytic cleavage by specific elastase-like enzymes. All the biological properties of TGF alpha and EGF are likely elicited by the binding of these ligands to the EGF receptor, therefore the biochemical cascade that follows activation of the EGF receptor tyrosine kinase is likely to be the same following activation of the receptor by either ligand.

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human, Mouse, Rabbit (Lapine), Rat
  • Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TGF-alpha.
  • Isotype: Rabbit Ig
  • Gene: P01135

Handling

  • Quantity: 0.1 mg
  • Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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