Product & ReviewsAntibodies
THEM4 Rabbit pAb
Product Details
- Cat. No.
- A15940
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
Western blot - THEM4 antibody (A15940)
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Description
Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
