Product & ReviewsAntibodies
Thyroid Hormone Receptor alpha1/alpha2 Antibody
Product Details
- Cat. No.
- 253228
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Thyroid hormones are essential for development of the central nervous system. Deficits in these hormones during development affect cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRa1, TRa2, TRb1 and TRb2. TRa1, TRb1 and TRb2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Dog (Canine), Human, Mouse, Rat
- Antigen: KLH-conjugated peptide encompassing a sequence within the N-term region of human thyroid hormone receptor, a1/a2-isotype.
- Clone: 2103
- Isotype: Mouse IgG1
- Gene: P10827
Handling
- Quantity: 0.1 ml
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Western Blotting (WB)