TIEG1 / KLF10 rabbit antibody (pAb)
Product Details
- Cat. No.
- 61117
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
TIEG1 / KLF10 (Transforming growth factor b-inducible early gene 1, Kruppel-like factor 10) is a transcriptional regulator involved in the control of cell growth. KLF10 binds to Sp1 / GC rich DNA sequences and can activate or repress the transcription of a number of genes. KLF10 is especially important for osteoblast function, including bone mineralization and support of osteoclast differentiation. KLF10 is rapidly induced by TGFb, bone morphogenetic protein, estrogen and epidermal growth factor. KLF10 plays a major role in TGFb-mediated inhibition of cell proliferation and inflammation and induction of apoptosis.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Isotype: IgG
Handling
- Quantity: 100 ul
- Storage: Antibodies in solution can be stored at -20C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Applications
- Western Blotting (WB)