Product & ReviewsAntibodies
TIGAR Antibody
Product Details
- Cat. No.
- 250533
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
TIGAR is a probable fructose-biphosphatase that lowers cellular levels of fructose 2,6-bisphosphate, thus blocking glycolysis and directing the pathway into the pentose phosphate shunt. TIGAR protects cells against reactive oxygen species. It is rapidly up-regulated by p53, and protects against p53-induced apoptosis. TIGAR is phosphorylated upon DNA damage, probably by ATM or ATR.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human, Mouse
- Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TIGAR.
- Isotype: Rabbit Ig
- Gene: Q9NQ88
Handling
- Quantity: 0.1 mg
- Storage: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- Western Blotting (WB)