Product & ReviewsAntibodies
TNF-alpha (2A9B) Antibody
Product Details
- Cat. No.
- 252734
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
TNF-alpha (Tumor necrosis factor alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: Recombinant Human TNF-alpha (BioSource company, Cat.No. PHC3013)
- Clone: 2A9B9
- Isotype: Mouse IgG1
- Gene: P01375, NP_000585
Handling
- Quantity: 0.1 mg
- Storage: Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Applications
- Western Blotting (WB)